Induced sputum in occupational lung diseases
نویسندگان
چکیده
منابع مشابه
Induced sputum in interstitial lung diseases.
PURPOSE OF REVIEW Induced sputum is a particularly useful procedure since it provides information on the cellular and molecular constituents in inflammation. Extensive work has demonstrated the application of induced sputum in the management of asthma, chronic obstructive pulmonary disease and chronic bronchitis, but less attention has been paid to its efficacy in diagnosing interstitial lung d...
متن کاملComparison of biomarkers in serum and induced sputum of patients with occupational asthma and chronic obstructive pulmonary disease
OBJECTIVES Occupational asthma and chronic obstructive pulmonary disease (COPD) are associated with the airway inflammatory process. The aim of this study was to compare the sputum and serum markers of inflammation in patients with occupational asthma and COPD. METHODS The study group included 20 patients with stable COPD, 24 patients with asthma, and 22 healthy subjects. Interleukin (IL)-6, ...
متن کاملPossible future of induced sputum in interstitial lung disease.
The search for noninvasive means of retrieving cells and soluble material from the lung has gained momentum over the past few years. Induced sputum is a particularly promising procedure since it provides specific information on both the cellular and soluble constituents in airways inflammation. It was first used to investigate lung cancer and respiratory infections [1, 2], and later to diagnose...
متن کاملInduced sputum as a diagnostic tactic in pulmonary diseases.
The induced sputum technique allows sampling of the airways in a non-invasive manner and thus offers a unique opportunity to identify biomarkers of potential clinical utility in respiratory medicine. Sputum cells were originally examined in stained smears and the procedure was applied in both research and clinical settings from the 1950s through the 1970s. The cells, recovered from spontaneous ...
متن کاملRedefining idiopathic interstitial lung disease into occupational lung diseases by analysis of chemical composition of inhaled dust particles in induced sputum and/or lung biopsy specimens.
There has been increased public awareness of the potential danger from exposure to hazardous dust in various occupations. This study aims to validate the qualitative analysis of scanning electron microscopy (SEM) of lung samples by 1) correlation of induced sputum (IS) findings to clinical findings, 2) comparing hazardous particles in IS to those in biopsied lung specimens, and 3) assessing whe...
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